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plenticrispr v2 containing sgrnas targeting ep300 and caprin2  (GenScript corporation)

 
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    GenScript corporation plenticrispr v2 containing sgrnas targeting ep300 and caprin2
    LINC00941 regulates <t>CAPRIN2</t> expression through DNA looping. A, CAPRIN2 expression after silencing LINC00941. B, CAPRIN1 expression after silencing LINC00941. C, Diagram of H3K27ac signals on LINC00941 and CAPRIN2 across different cancer types. LINC00941 promoter and CAPRIN2 promoter were labelled with yellow. Sites used for DNA‐DNA interaction detection were shown in the bottom. D, 3C results of DNA interaction frequency between anchor and other DNA sites. E, 3C results of DNA interaction frequency between anchor and other DNA sites before and after knocking down CTCF. F, Western blot results of CTCF. GAPDH was used as control. Relative CAPRIN2 (G) and LINC00941 expression (H) after deleting CTCF. * P < .05, ** P < .01, *** P < .001
    Plenticrispr V2 Containing Sgrnas Targeting Ep300 And Caprin2, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plenticrispr+v2+containing+sgrnas+targeting+ep300+and+caprin2/plenticrispr+v2+containing+sgrnas+targeting+ep300+and+caprin2/pmc07521336-76-7-11
    Average 90 stars, based on 1 article reviews
    plenticrispr v2 containing sgrnas targeting ep300 and caprin2 - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway"

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway

    Journal: Journal of Cellular and Molecular Medicine

    doi: 10.1111/jcmm.15667

    LINC00941 regulates CAPRIN2 expression through DNA looping. A, CAPRIN2 expression after silencing LINC00941. B, CAPRIN1 expression after silencing LINC00941. C, Diagram of H3K27ac signals on LINC00941 and CAPRIN2 across different cancer types. LINC00941 promoter and CAPRIN2 promoter were labelled with yellow. Sites used for DNA‐DNA interaction detection were shown in the bottom. D, 3C results of DNA interaction frequency between anchor and other DNA sites. E, 3C results of DNA interaction frequency between anchor and other DNA sites before and after knocking down CTCF. F, Western blot results of CTCF. GAPDH was used as control. Relative CAPRIN2 (G) and LINC00941 expression (H) after deleting CTCF. * P < .05, ** P < .01, *** P < .001
    Figure Legend Snippet: LINC00941 regulates CAPRIN2 expression through DNA looping. A, CAPRIN2 expression after silencing LINC00941. B, CAPRIN1 expression after silencing LINC00941. C, Diagram of H3K27ac signals on LINC00941 and CAPRIN2 across different cancer types. LINC00941 promoter and CAPRIN2 promoter were labelled with yellow. Sites used for DNA‐DNA interaction detection were shown in the bottom. D, 3C results of DNA interaction frequency between anchor and other DNA sites. E, 3C results of DNA interaction frequency between anchor and other DNA sites before and after knocking down CTCF. F, Western blot results of CTCF. GAPDH was used as control. Relative CAPRIN2 (G) and LINC00941 expression (H) after deleting CTCF. * P < .05, ** P < .01, *** P < .001

    Techniques Used: Expressing, Western Blot, Control

    CAPRIN2 up‐regulation promotes OSCC cells proliferation. A, Western blot results of CAPRIN2 expression from OSCC cells, normal oral keratinocytes HOK and normal tongue tissue. B, RT‐qPCR results of CAPRIN2 between patient tumour tissues and normal tissues. C, Correlation analysis of LINC00941 and CAPRIN2 expression between patient tumour tissues and normal tissues. D, Western blot results of CAPRIN2. GAPDH was used as control. E, Cell growth after deleting CAPRIN2. F, Cell cycle detection after deleting CAPRIN2. * P < .05, ** P < .01, *** P < .001
    Figure Legend Snippet: CAPRIN2 up‐regulation promotes OSCC cells proliferation. A, Western blot results of CAPRIN2 expression from OSCC cells, normal oral keratinocytes HOK and normal tongue tissue. B, RT‐qPCR results of CAPRIN2 between patient tumour tissues and normal tissues. C, Correlation analysis of LINC00941 and CAPRIN2 expression between patient tumour tissues and normal tissues. D, Western blot results of CAPRIN2. GAPDH was used as control. E, Cell growth after deleting CAPRIN2. F, Cell cycle detection after deleting CAPRIN2. * P < .05, ** P < .01, *** P < .001

    Techniques Used: Western Blot, Expressing, Quantitative RT-PCR, Control

    LINC00941/CAPRIN2 activates canonical WNT signaling pathway. A, Western blot results CAPRIN2, β‐catenin, phosphorylated LRP6 (p‐LRP6) and LRP6 after deleting CAPRIN2 or silencing LINC00941. GAPDH was used as control. B, RT‐qPCR detects WNT canonical downstream target genes MYC, SOX9 and CCND1 and WNT non‐canonical downstream gene CaMKII and WNT5a expression after deleting CAPRIN2 or silencing LINC00941. C, MYC expression after silencing LINC00941 in the presence or absence of CAPRIN2. D, Detection of cell growth after silencing LINC00941 in the presence or absence of 30 ng/mL WNT3a. * P < .05, ** P < .01, *** P < .001
    Figure Legend Snippet: LINC00941/CAPRIN2 activates canonical WNT signaling pathway. A, Western blot results CAPRIN2, β‐catenin, phosphorylated LRP6 (p‐LRP6) and LRP6 after deleting CAPRIN2 or silencing LINC00941. GAPDH was used as control. B, RT‐qPCR detects WNT canonical downstream target genes MYC, SOX9 and CCND1 and WNT non‐canonical downstream gene CaMKII and WNT5a expression after deleting CAPRIN2 or silencing LINC00941. C, MYC expression after silencing LINC00941 in the presence or absence of CAPRIN2. D, Detection of cell growth after silencing LINC00941 in the presence or absence of 30 ng/mL WNT3a. * P < .05, ** P < .01, *** P < .001

    Techniques Used: Western Blot, Control, Quantitative RT-PCR, Expressing

    Related Articles

    Expressing:

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway
    Article Snippet: pLentiCRISPR v2 containing sgRNAs targeting EP300 and CAPRIN2 were purchased from GenScript, USA. .. O

    Western Blot:

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway
    Article Snippet: pLentiCRISPR v2 containing sgRNAs targeting EP300 and CAPRIN2 were purchased from GenScript, USA. .. O

    Control:

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway
    Article Snippet: pLentiCRISPR v2 containing sgRNAs targeting EP300 and CAPRIN2 were purchased from GenScript, USA. .. O

    Quantitative RT-PCR:

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway
    Article Snippet: pLentiCRISPR v2 containing sgRNAs targeting EP300 and CAPRIN2 were purchased from GenScript, USA. .. O



    Similar Products

    plenticrispr v2 containing sgrnas targeting ep300 and caprin2  (GenScript corporation)
    90
    GenScript corporation plenticrispr v2 containing sgrnas targeting ep300 and caprin2
    LINC00941 regulates <t>CAPRIN2</t> expression through DNA looping. A, CAPRIN2 expression after silencing LINC00941. B, CAPRIN1 expression after silencing LINC00941. C, Diagram of H3K27ac signals on LINC00941 and CAPRIN2 across different cancer types. LINC00941 promoter and CAPRIN2 promoter were labelled with yellow. Sites used for DNA‐DNA interaction detection were shown in the bottom. D, 3C results of DNA interaction frequency between anchor and other DNA sites. E, 3C results of DNA interaction frequency between anchor and other DNA sites before and after knocking down CTCF. F, Western blot results of CTCF. GAPDH was used as control. Relative CAPRIN2 (G) and LINC00941 expression (H) after deleting CTCF. * P < .05, ** P < .01, *** P < .001
    Plenticrispr V2 Containing Sgrnas Targeting Ep300 And Caprin2, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/plenticrispr+v2+containing+sgrnas+targeting+ep300+and+caprin2/plenticrispr+v2+containing+sgrnas+targeting+ep300+and+caprin2/pmc07521336-76-7-11
    Average 90 stars, based on 1 article reviews
    plenticrispr v2 containing sgrnas targeting ep300 and caprin2 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    LINC00941 regulates CAPRIN2 expression through DNA looping. A, CAPRIN2 expression after silencing LINC00941. B, CAPRIN1 expression after silencing LINC00941. C, Diagram of H3K27ac signals on LINC00941 and CAPRIN2 across different cancer types. LINC00941 promoter and CAPRIN2 promoter were labelled with yellow. Sites used for DNA‐DNA interaction detection were shown in the bottom. D, 3C results of DNA interaction frequency between anchor and other DNA sites. E, 3C results of DNA interaction frequency between anchor and other DNA sites before and after knocking down CTCF. F, Western blot results of CTCF. GAPDH was used as control. Relative CAPRIN2 (G) and LINC00941 expression (H) after deleting CTCF. * P < .05, ** P < .01, *** P < .001

    Journal: Journal of Cellular and Molecular Medicine

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway

    doi: 10.1111/jcmm.15667

    Figure Lengend Snippet: LINC00941 regulates CAPRIN2 expression through DNA looping. A, CAPRIN2 expression after silencing LINC00941. B, CAPRIN1 expression after silencing LINC00941. C, Diagram of H3K27ac signals on LINC00941 and CAPRIN2 across different cancer types. LINC00941 promoter and CAPRIN2 promoter were labelled with yellow. Sites used for DNA‐DNA interaction detection were shown in the bottom. D, 3C results of DNA interaction frequency between anchor and other DNA sites. E, 3C results of DNA interaction frequency between anchor and other DNA sites before and after knocking down CTCF. F, Western blot results of CTCF. GAPDH was used as control. Relative CAPRIN2 (G) and LINC00941 expression (H) after deleting CTCF. * P < .05, ** P < .01, *** P < .001

    Article Snippet: pLentiCRISPR v2 containing sgRNAs targeting EP300 and CAPRIN2 were purchased from GenScript, USA.

    Techniques: Expressing, Western Blot, Control

    CAPRIN2 up‐regulation promotes OSCC cells proliferation. A, Western blot results of CAPRIN2 expression from OSCC cells, normal oral keratinocytes HOK and normal tongue tissue. B, RT‐qPCR results of CAPRIN2 between patient tumour tissues and normal tissues. C, Correlation analysis of LINC00941 and CAPRIN2 expression between patient tumour tissues and normal tissues. D, Western blot results of CAPRIN2. GAPDH was used as control. E, Cell growth after deleting CAPRIN2. F, Cell cycle detection after deleting CAPRIN2. * P < .05, ** P < .01, *** P < .001

    Journal: Journal of Cellular and Molecular Medicine

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway

    doi: 10.1111/jcmm.15667

    Figure Lengend Snippet: CAPRIN2 up‐regulation promotes OSCC cells proliferation. A, Western blot results of CAPRIN2 expression from OSCC cells, normal oral keratinocytes HOK and normal tongue tissue. B, RT‐qPCR results of CAPRIN2 between patient tumour tissues and normal tissues. C, Correlation analysis of LINC00941 and CAPRIN2 expression between patient tumour tissues and normal tissues. D, Western blot results of CAPRIN2. GAPDH was used as control. E, Cell growth after deleting CAPRIN2. F, Cell cycle detection after deleting CAPRIN2. * P < .05, ** P < .01, *** P < .001

    Article Snippet: pLentiCRISPR v2 containing sgRNAs targeting EP300 and CAPRIN2 were purchased from GenScript, USA.

    Techniques: Western Blot, Expressing, Quantitative RT-PCR, Control

    LINC00941/CAPRIN2 activates canonical WNT signaling pathway. A, Western blot results CAPRIN2, β‐catenin, phosphorylated LRP6 (p‐LRP6) and LRP6 after deleting CAPRIN2 or silencing LINC00941. GAPDH was used as control. B, RT‐qPCR detects WNT canonical downstream target genes MYC, SOX9 and CCND1 and WNT non‐canonical downstream gene CaMKII and WNT5a expression after deleting CAPRIN2 or silencing LINC00941. C, MYC expression after silencing LINC00941 in the presence or absence of CAPRIN2. D, Detection of cell growth after silencing LINC00941 in the presence or absence of 30 ng/mL WNT3a. * P < .05, ** P < .01, *** P < .001

    Journal: Journal of Cellular and Molecular Medicine

    Article Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway

    doi: 10.1111/jcmm.15667

    Figure Lengend Snippet: LINC00941/CAPRIN2 activates canonical WNT signaling pathway. A, Western blot results CAPRIN2, β‐catenin, phosphorylated LRP6 (p‐LRP6) and LRP6 after deleting CAPRIN2 or silencing LINC00941. GAPDH was used as control. B, RT‐qPCR detects WNT canonical downstream target genes MYC, SOX9 and CCND1 and WNT non‐canonical downstream gene CaMKII and WNT5a expression after deleting CAPRIN2 or silencing LINC00941. C, MYC expression after silencing LINC00941 in the presence or absence of CAPRIN2. D, Detection of cell growth after silencing LINC00941 in the presence or absence of 30 ng/mL WNT3a. * P < .05, ** P < .01, *** P < .001

    Article Snippet: pLentiCRISPR v2 containing sgRNAs targeting EP300 and CAPRIN2 were purchased from GenScript, USA.

    Techniques: Western Blot, Control, Quantitative RT-PCR, Expressing